MID-TERM ABORTION INDUCED IN SHEEP BY SYNTHETIC CORTICOIDS

in Reproduction

Premature parturition in sheep following administration of synthetic corticoids is now well documented (Van Rensburg, 1967; Bosc, 1970; Skinner, van Blom, Gouws & Jöchle, 1970; Fylling, 1971). In the cow, both premature parturition (Adams, 1969; Hansen & Christiansen, 1971; Karg, Böhm, Günzler & Müller, 1971; L. E. Edquist, personal communication) and mid-term abortion (L. E. Edquist, personal communication) have been reported following such treatment. Induction of abortion in sheep by synthetic corticoids has not been reported so far. This paper presents a study on the effect of dexamethasone given to ewes during mid-term pregnancy.

Five ewes of the Dala breed, all 80 days pregnant, were included in the investigation. The mean gestational period in this breed is 148 days. The animals received intramuscular injections of 2·5 mg dexamethasone four times

No.5 84 86 88 Days of

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    Society for Reproduction and Fertility

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