Special series on Impact of Real-Life Environmental Exposures on Reproduction

in Reproduction
Authors:
Jodi A Flaws J Flaws, Comparative Biosciences, University of Illinois Urbana-Champaign, 61802, 61802, United States

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Vasantha Padmanabhan V Padmanabhan, Pediatrics, University of Michigan, Ann Arbor, 48109-5718, United States

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Correspondence: Vasantha Padmanabhan, Email: vasantha@umich.edu
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Environmental exposures to endocrine disrupting chemicals (EDCs), air pollution, biosolids, fracking materials, some pharmaceutical agents, and heat stress adversely affect reproductive health and exert long-ranging effects on maternal, paternal, and child health (Gore et al. 2015; Brehm & Flaws 2019; Gonsioroski et al. 2020; Peretz et al. 2014; Padmanabhan et al. 2021). Exposure to EDCs is of particular concern because EDCs mimic endogenous hormones and interfere with the physiological functions of reproductive organs. Disruption of normal endocrine homeostasis by EDCs affects fertility and causes reproductive disorders as well as premature reproductive senescence. Further, the annual costs for disorders due to EDC exposure in the United States and the European Union are estimated to be the billions of dollars (Attina et al. 2016; Hunt et al. 2016; Hauser et al. 2015).

 

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