not in spermatogonia, spermatocytes, or Sertoli cells in seminiferous tubules ( Fig. 3 A and B). KISS1R was rarely detected in Leydig cells of the interstitial testicular compartment ( Fig. 2 D), but ∼12.4±4.9% of total Leydig cells (mean± s.d .; n =7
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Meng-Chieh Hsu, Jyun-Yuan Wang, Yue-Jia Lee, De-Shien Jong, Kuan-Hao Tsui, and Chih-Hsien Chiu
Cheryl J Ashworth, Charis O Hogg, Cindy W F Hoeks, Ramona D Donald, W Colin Duncan, Alistair B Lawrence, and Kenny M D Rutherford
-natal stress or post-natal pain the number of germ cells, seminiferous tubules, Leydig cells or Sertoli cells, when expressed either per total area of testis tissue ( Table 5 ) or as a percentage of the total cells. However, the number and percentage of Leydig
Mónica P Recabarren, Pedro P Rojas-Garcia, Ralf Einspanier, Vasantha Padmanabhan, Teresa Sir-Petermann, and Sergio E Recabarren
450scc, and 3β-HSD (3BHSD) in whole testicular tissue and the expression of P450c17, P450scc, 17BHSD type 3, and 3BHSD in Leydig cells cultured before and after an human chorionic gonadotrophin (hCG) challenge. Results Pituitary LH responsiveness 20
Qianqian Yang, Binfang Ma, Huilian Qiao, He Ma, Yuhang Dong, Liang Cao, Jing Ma, and Zhen Li
oestrogens play a key role in the male reproductive system. Leydig cells (LCs) in the adult testis have long been considered as the main site of conversion of androgens into oestrogens, although Sertoli cells (SCs) of prepuberty and germ cells can generate
P Browne, N J Place, J D Vidal, I T Moore, G R Cunha, S E Glickman, and A J Conley
functional as endocrine organs ( Wilson et al. 1995 ). Testosterone secretion by the fetal Leydig cells stabilizes the Wolffian ducts, ensuring complete male duct formation. Testosterone is also converted to dihydrotestosterone (DHT) within the primordial
Yongmei Chen, Huizhen Wang, Nan Qi, Hui Wu, Weipeng Xiong, Jing Ma, Qingxian Lu, and Daishu Han
A and B, TYRO3 and AXL were localized to Sertoli cells; MER was detected both in interstial Leydig cells (LCs) and Sertoli cells (upper panel). In order to confirm the cell-specific expression of TAM RTKs, we performed immunocytochemistry on the
A Wagner and R Claus
testes the total volume of the Leydig cell compartment is unusually high and represents about one-third of the total testis volume ( Groth & Claus 1977 ). In addition, an ABP could not be demonstrated ( Jegou & Le Gac-Jegou 1978 ), but testosterone
Sung Tae Kim and Kelle H Moley
, prostate, intestine, and testis ( Carayannopoulos et al . 2000 , Doege et al . 2000 , Gomez et al . 2006 ). Currently, we have confirmed that SLC2A8 is highly expressed in the Leydig cells as well as in the innermost cells of the seminiferous tubules
Niels A Hammer, Thomas v O Hansen, Anne Grete Byskov, Eva Rajpert-De Meyts, Marie Louise Grøndahl, Helle E Bredkjær, Ulla M Wewer, Jan Christiansen, and Finn C Nielsen
during gonadal development and with gender differences. Moreover, in the testis IMP1 and IMP3 are germ-cell specific, whereas IMP2 appears to be expressed primarily in Leydig cells. Materials and Methods Human and mouse
Isabel Barranco, Cristina Perez-Patiño, Asta Tvarijonaviciute, Inmaculada Parrilla, Alejandro Vicente-Carrillo, Manuel Alvarez-Rodriguez, Jose J Ceron, Emilio A Martinez, Heriberto Rodriguez-Martinez, and Jordi Roca
. 2011 ), have partially addressed this issue, both focused exclusively to the testis, showing that Leydig cells are capable of synthesising PON1. However, the Leydig cells seem not to be the only source of SP-PON1, particularly in sires of livestock
