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The β-glucuronidase and esterase content of rat testes after X-ray treatment has been studied.

It was found that together with the tubular damage induced by the radiation there was a definite and progressive increase of β-glucuronidase activity. Variations in the acetic and valeric esterase activities were not clearly defined.

As the radiation causes tubular cell destruction while the Leydig interstitial cells remain apparently undamaged, the authors think that the enzymatic variations may be related to a hyperfunctional state of the interstitial cells during the destructive action of the X-rays on the tubular epithelium.