Summary. The protein patterns of fetal rat gonads (14½–21½ days of gestation) were examined by SDS gel electrophoresis. Male gonads contained more protein components at all stages.
A. P. Banerji, A. K. Dubey, S. Sarkar, and P. N. Shah
S. Sarkar, A. K. Dubey, A. P. Banerji, and P. N. Shah
Summary. The isoenzymes of LDH were detected by polyacrylamide gel electrophoresis. The M and H LDH subunits were present in gonads of both sexes from Day 14½p.c. and there was some variation with increased gestation. From Day 20 after birth two specific LDH-X bands (X1 and X2) were evident in the spermatocyte-rich fraction, but not in those of the Sertoli and Leydig cell fractions or those of the ovary.
V. Puri, G. F. X. David, A. K. Dubey, C. P. Puri, and T. C. Anand Kumar
Summary. Intranasal administration of norethisterone at a daily dose of 9 μg between Days 5 and 14 of the menstrual cycles blocked ovulation in 10 out of 17 adult female monkeys. Serum concentrations of hormones indicated that ovulation was blocked due to a suppression of the mid-cycle, oestradiol-induced LH surge. Ovarian follicular activity in the treated menstrual cycles was not affected by norethisterone but there was a marked delay in the onset of the mid-cycle oestradiol surge in most of the treated animals. The duration of the menstrual cycle length after the oestradiol peak was significantly reduced in all the treated monkeys, indicative of a shortened luteal phase.