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ANNE D. VICKERS

Summary.

Chromosomes were studied in mouse embryos and foetuses recovered after superovulation. The spontaneous incidence of chromosomal anomalies was 2·6%; a delay of 7 to 13 hr before fertilization produced 3·9% anomalies. The most striking feature was a nine-fold increase in the incidence of triploidy after delayed fertilization. The chromosomal anomalies included isochromosomes and minute chromosomes. Some anomalous individuals survive implantation and the fate of such foetuses is discussed.

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ANNE D. VICKERS

Summary.

The primary sex-ratio of the PDE mouse, assessed by chromosomal analysis of embryos recovered after superovulation, was not significantly different from 100, nor was it significantly affected by delayed fertilization. The sex-ratio was assessed after implantation and at full term. There was no evidence of sex-selective mortality operating at any stage of gestation.

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ANNE D. VICKERS

Summary.

Ninety-eight mouse blastocysts were sexed by means of chromosome analysis. Forty-nine were males and forty-nine were females, a sex-ratio of 50%. It is concluded that there is no reason to believe that the sex-ratio at conception in the mouse is not 50%.

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ANNE D. VICKERS

Summary.

Sex chromatin is present in 67 to 90% of the ectodermal cell nuclei in the female mouse amnion. A similar body is found in 2 to 15% of these nuclei in the male. This criterion is a reliable indicator of the sex of the foetus from the 11th day of gestation onwards.