The infusion of solutions of iodine into the uterus through the cervical canal has been practised as a therapeutic measure in certain cases of infertility in farm animals. Little is known about the possible mode of action of such treatment, though Ekman, Holmberg, Settergren & Thorell (1965) have shown that iodide is rapidly absorbed from the uterine lumen in the cow and have suggested that systemic as well as local effects might be involved. On the other hand, iodide has been shown to be present in the cervical mucus in women at a concentration above that in plasma (see Brown-Grant, 1961, for references) and in the rat, a very high concentration of iodide relative to plasma has been demonstrated in the oviduct and
G. J. R. HOVELL, R. CULLEN and K. BROWN-GRANT
G. J. R. HOVELL, G. M. ARDRAN, D. M. ESSENHIGH and J. C. SMITH
Observations on the urogenital tract were made radiologically in six rams. Contrast medium was first introduced to the urethra or vas deferens before electrical stimulation was applied per rectum and later to the vas during a series of stimuli to induce ejaculation.
Without stimulation, contrast medium reaching the pelvic urethra from either the penile urethra or the ampulla was generally expelled in a retrograde manner to the bladder, while residual material in the penile urethra was voided.
Ejaculation took place only during pauses between stimuli, fluid being discharged from the ampulla straight through into the penile urethra. This main discharge was followed by some reflux of fluid from the pelvic urethra to the bladder. At rest, no fluid remained in either the pelvic or the penile urethra.