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R. D. HODGES and H. G. HANLEY

Summary.

In a series of epididymides obtained from infertile men, a number of specimens were found to possess malformations of the duct epithelium. These consisted of epithelial vesicles and/or epithelial hyperplasia and frequently gave rise to considerable disruption of the epithelium. The probable sequence of development of the intra-epithelial vesicles from vacuolated basal cells to large vesicles and their subsequent degeneration has been described. The possible causes of these defects are discussed in the light of previous findings in animals.