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K. L. Grieve and K. E. Kendle

Summary. The transport of embryos in mouse oviducts incubated in vitro was studied for 16 h. Successful embryo transport occurred in oviducts incubated from Day 2 or Day 3 of pregnancy, and the process was dependent on the availability of calcium from the incubation medium. This indicates that this phase of transport is a result of smooth muscle activity. Embryo transport did not occur in oviducts perfused from Day 1 of pregnancy.

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K. L. Grieve, J. M. Henwood, and K. E. Kendle

Summary. Combined ovariectomy and adrenalectomy retarded mouse embryo transport while either operation alone did not. Serum progesterone levels were reduced after ovariectomy and after the combined operation but detectable levels were still present on Day 4 following both procedures. Embryo transport was also retarded after administration of testosterone propionate. This effect was abolished by progesterone and was not mimicked by 5α-dihydrotestosterone. From these results it is concluded that progesterone influences embryo transport and that androgenic effects are probably a result of antagonism of progesterone.