Experimentally induced extra-uterine pregnancies (eup) in virgin mice did not stop the oestrous cycle, inhibit mating with ensuing pregnancy or stimulate the corpora lutea sufficiently to produce progestational changes in the genital tract. The eup, however, caused changes typically associated with pregnancy in the adrenal cortex and mammary glands. In the former the X-zone either completely disappeared or underwent degenerative changes. The mammary glands showed definite lobulo-alveolar development, not affected by adrenalectomy, but abolished both by ovariectomy and hypophysectomy.
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