EFFECT OF ACUTE OVARIECTOMY ON MATING IN THE CYCLIC RAT

in Reproduction
In female rats, uterine weight increases early in pro-oestrus (Astwood, 1939; Schwartz, 1964), behavioural oestrus occurs during the early evening of prooestrus (Boling, Blandau, Soderwall & Young, 1941) and pituitary lh content drops from a maximum at pro-oestrus to a minimum on the morning of oestrus (Schwartz & Bartosik, 1962; Schwartz, 1964), by which time ovulation and vaginal cornification have occurred. A great deal of evidence suggests that these changes are due to a cyclic increase in ovarian secretion (see Schwartz, 1964). In a recent investigation of the timing of this ovarian secretion it was demonstrated that ovariectomy at 16.00 hours on the day before pro-oestrus, but not at 10.00 hours on the morning of pro-oestrus, blocked vaginal cornification; however, it was necessary to perform the ovariectomy at 10.00 hours on the day before

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