EFFECT OF MATERNAL AGE ON VIABILITY OF OVA AND UTERINE SUPPORT OF PREGNANCY IN MICE
in ReproductionSearch for other papers by GEORGE B. TALBERT in
Current site
Google Scholar
PubMed
Search for other papers by P. L. KROHN in
Current site
Google Scholar
PubMed
Summary.
The technique of ova transplantation was used to study the causes of the decline in litter size in ageing mice. Only 14% of morulae and blastocysts obtained from the uteri of young donors survived to term when transplanted into the uteri of old hosts (13 to 24 months of age), whereas 48% survived in young hosts (2 to 7 months of age). A slightly higher percentage of grossly abnormal ova was recovered on the 4th day of pregnancy from the uteri of old mice than from young mice (13% compared with 5%). However, normal-appearing morulae and blastulae from old mice survived as well as those from young mice when transferred into uteri of young hosts. It was concluded that the initial decline in litter size in aged mice is probably due to an unfavourable uterine environment.
Reproduction is committed to supporting researchers in demonstrating the impact of their articles published in the journal.
The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.
More information is on the Reasons to publish page.
| Sept 2018 onwards | Past Year | Past 30 Days | |
|---|---|---|---|
| Full Text Views | 655 | 279 | 15 |
| PDF Downloads | 186 | 67 | 4 |
Online ISSN: 1741-7899
Print ISSN: 1470-1626
Strengthening biomedical communities
to advance science and health
CONTACT US
Bioscientifica Ltd | Starling House | 1600 Bristol Parkway North | Bristol BS34 8YU | UK
Bioscientifica Ltd | Registered in England no 3190519