THE INITIATION OF THE DECIDUAL CELL REACTION IN THE UTERUS OF THE AGED MOUSE
in ReproductionSearch for other papers by C. A. FINN in
Current site
Google Scholar
PubMed
Summary.
Groups of old and young mice were ovariectomized and injected with hormones on a schedule to mimic the endocrine conditions of pregnancy. An artificial decidual stimulus, either trauma or the intraluminal injection of arachis oil, was applied to the left horn of the uterus and the decidual response assessed.
Following trauma, the uteri of the old mice produced significantly smaller deciduomata than those produced in the young mice. After the injection of oil there was no decidual response in the old mice, whereas in the young mice there was a good reaction in seven out of eleven animals.
It is concluded that the ability to form decidual tissue is considerably reduced in old mice, and it is suggested that this may be a significant factor in the senile reduction of litter size.
Reproduction is committed to supporting researchers in demonstrating the impact of their articles published in the journal.
The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.
More information is on the Reasons to publish page.
| Sept 2018 onwards | Past Year | Past 30 Days | |
|---|---|---|---|
| Full Text Views | 461 | 238 | 20 |
| PDF Downloads | 140 | 33 | 3 |
Online ISSN: 1741-7899
Print ISSN: 1470-1626
Strengthening biomedical communities
to advance science and health
CONTACT US
Bioscientifica Ltd | Starling House | 1600 Bristol Parkway North | Bristol BS34 8YU | UK
Bioscientifica Ltd | Registered in England no 3190519