Luteinizing hormone (lh) activity in blood was assessed by the ovarian cholesterol depletion (ocd) method and oestrogens were estimated chemically in the urine of seven sows before and during oestrus. In three sows, peritoneal cannulation permitted the time of ovulation to be related to lh and oestrogen determinations. The findings suggest a marked elevation of blood lh activity coincident with a peak of urinary oestrogen excretion, and occurring 40 to 48 hr before the time of ovulation.
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