ENDOCRINE ASPECTS OF EGG IMPLANTATION IN THE RAT
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Psychoyos (1961) examined the development of eggs which had been collected from donor rats, that were either normally pregnant or undergoing delayed implantation, and then transferred to the uteri of spayed and progesterone treated recipients. It was found that implantation of such eggs occurred only after the recipient had been treated with oestrogen. Later, he established the importance of the timing of oestrogen treatment in relation to egg transfer (Psychoyos, 1963). We have now examined the fate of blastocysts transferred to the uteri of rats, which were treated in several different ways, so as to obtain further information on the hormonal conditions affecting implantation.
A total of sixty-five adult hooded rats was used as recipients. Eggs were obtained from donors during the morning of Day 5 of pregnancy (Day 1 = day on which spermatozoa
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