It has been known for many years (Warwick, Berry & Horlacher, 1932, 1933, 1934) that goats readily conceive when inseminated with ram semen but that the hybrid embryos fail to survive beyond the second month of pregnancy. Berry (1938) concluded from an examination of cells from the hybrid amnion that the death of the foetus was unlikely to be due to abnormalities of cell division. The sheep has fifty-four chromosomes comprising six metacentric chromosomes and forty-eight acrocentric chromosomes, while the goat has sixty chromosomes all of which are acrocentric. Berry found the chromosome number of the hybrid to be fifty-seven, but he noted only two metacentric chromosomes.
Berry's illustrations give clear evidence that the techniques available to him yielded preparations greatly inferior to those produced by
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