DELAYED IMPLANTATION IN THE SPAYED, PROGESTERONE TREATED ADULT MOUSE

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Authors:
K. YOSHINAGA
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and
C. E. ADAMS
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DOI:
https://doi.org/10.1530/jrf.0.0120593
Volume/Issue:
Volume 12: Issue 3
Page Range:
593–595
Article Type:
Research Article
Online Publication Date:
Dec 1966
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The influence of the time of spaying on the occurrence of delayed implantation has been intensively studied in the rat. Although it was originally reported that early spaying (Day 1 or 2 of pregnancy) followed by progesterone treatment did not lead to a delay in implantation, whereas spaying at a later stage (Day 4) did (Canivenc, Laffargue & Mayer, 1956; Cochrane & Meyer, 1957), further work on rats revealed that spaying before Day 4 generally resulted in delayed implantation (Psychoyos & Alloiteau, 1962; Nutting & Meyer, 1963; Mayer, 1963). Failure to observe delayed implantation more universally in the early experiments has been ascribed in part to incomplete ovariectomy. As the influence of the time of spaying on implantation has apparently not been examined in the adult mouse, the present work was undertaken. Endocrinolo

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Print ISSN:
1470-1626
Online ISSN:
1741-7899