THE EFFECT OF CLOMIPHENE ON SPERMATOGENESIS AND HORMONE EXCRETION IN A PATIENT WITH KLINEFELTER'S SYNDROME

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Authors:
G. L. FOSS
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,
E. T. BELL
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,
F. J. W. LEWIS
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J. A. LORAINE
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, and
B. R. POLLARD
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DOI:
https://doi.org/10.1530/jrf.0.0130315
Volume/Issue:
Volume 13: Issue 2
Page Range:
315–320
Article Type:
Research Article
Online Publication Date:
Apr 1967
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Summary.

The effect of clomiphene on the sperm count and hormone excretion is described in a patient with Klinefelter's syndrome, having a 47 XXY karyotype, and in whom a testicular biopsy showed small areas of spermatogenesis.

Clomiphene stimulated the production of morphologically normal motile spermatozoa in the absence of any marked effect on hormone output.

Possible explanations for these findings are discussed.

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Sept 2018 onwards Past Year Past 30 Days
Full Text Views 401 213 24
PDF Downloads 422 180 19

 

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Print ISSN:
1470-1626
Online ISSN:
1741-7899