The practice of AID designed to compensate for male sterility provides otherwise inaccessible data concerning the reproductive potential of nulligravidae in the general population. In the present analysis of 431 cases, preliminary investigation revealed a 76% incidence of unsuspected infecundity, the commonest factor being cervical dysfunction. Between 1955 and 1962 the conception rate increased from approximately 58% in a former series (1944–54) to 67%. The conception rate was higher in those receiving preliminary treatment than in the stigma-free cases, reflecting the rapid augmentation of diagnostic and therapeutic measures.
The abortion rate over the whole period of 18 years remained constant, possibly revealing the irreducible incidence of embryological abnormality.
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