Decidual cell reaction (DCR) of the endometrium to mechanical trauma applied on the 4th day of pseudopregnancy was compared in two inbred strains KE and KP, F1 hybrids and outbred mice. There was no difference between hybrid and outbred females. Mice from the KE strain had stronger reaction than F1 or outbred animals, while KP females, which have low fertility, had significantly smaller DCR. Uterine sensitivity to trauma on the 3rd, 4th or 5th day of pseudopregnancy was compared in KE and KP females. It was concluded that the relatively low and prolonged sensitivity of the uterus to mechanical stimuli in the KP strain may indicate an oestrogen deficiency.
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