EFFECT OF ALKANE SULPHONIC ESTERS ON OVARIAN DEVELOPMENT AND FUNCTION IN THE RAT

in Reproduction

Summary.

Closely related members of a homologous series of alkane sulphonic esters were administered to pregnant rats and their effect on oogenesis and fertility of female offspring studied. A marked antifertility action due to the diesters n = 1, 3, 4 and the branched chain monoester isopropyl methanesulphonate was referable to interference with oogonia. Methyl and ethyl monoesters also had an antifertility action although their effect was less evident.

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     An official journal of

    Society for Reproduction and Fertility

 

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