AGE-DEPENDENT CHANGES IN THE PITUITARY— GONADAL RELATIONSHIP

in Reproduction
Author:
A. P. LABHSETWAR
Search for other papers by A. P. LABHSETWAR in
Current site
Google Scholar
PubMed Close
DOI:
https://doi.org/10.1530/jrf.0.0200021
Volume/Issue:
Volume 20: Issue 1
Page Range:
21–28
Article Type:
Research Article
Online Publication Date:
Oct 1969
Free access

Sign up for journal news

Summary.

Pituitary stores of fsh and lh were determined in female rats of ages ranging from 12 to 14 days (24 g body weight) to an estimated 280 days (>375 g body weight). The aim was to study the endocrine basis for lack of ovarian compensatory hypertrophy in the aged rat. Both the concentration (μg/mg) and total content (μg/gland) of fsh in the pituitary glands of aged rats were two to three times higher than those in the glands from the adult rats (60 to 180 days old and weighing 200 to 300 g). A similar but less marked tendency was present for lh.

These results support the view that lack of ovarian compensatory hypertrophy in the aged rat is due to a decline in the output of fsh and lh from, but not due to deficiency of gonadotrophins in, the pituitary gland of the aged rat.

Reproduction is committed to supporting researchers in demonstrating the impact of their articles published in the journal.

The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.

More information is on the Reasons to publish page.

Sept 2018 onwards Past Year Past 30 Days
Full Text Views 108 32 9
PDF Downloads 20 13 3

 

  • Collapse
  • Expand
Print ISSN:
1470-1626
Online ISSN:
1741-7899