There is some evidence that atropine interferes with pharmacologically induced ejaculation in the mouse (Loewe, 1938; Loewe & Puttuck, 1953) and alters the physical and chemical composition of semen of other animals (Dziuk & Norton, 1962; Dziuk & Mann, 1963). Very little, however, is known about the effect of adrenaline on the composition of semen, and of adrenaline and atropine on the morphology of spermatozoa. The following experiment was conducted to determine if there was any effect of the two drugs on the morphology of mouse spermatozoa.Sixty colony-bred, adult, male albino mice (original stock from Italy and Germany) were allotted at random to three equal groups of twenty animals. One of the groups served as a control, and the control mice did not receive injections of saline. In another group, each mouse was given 0·72 mg atropine sulphate (B.D.H.) in 1·2 ml saline solution. In the third group,
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