DIFFERENTIATION OF RABBIT SPERM ANTIGENS FROM THOSE OF SEMINAL PLASMA

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Author:
ALAN G. HUNTER
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DOI:
https://doi.org/10.1530/jrf.0.0200413
Volume/Issue:
Volume 20: Issue 3
Page Range:
413–418
Article Type:
Research Article
Online Publication Date:
Dec 1969
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Summary.

Sperm-specific and sperm-coating antigens in rabbit seminal constituents were studied using agar-gel diffusion and immuno-electrophoresis. The antigenicity of ejaculated rabbit spermatozoa was due to two glycoprotein sperm-specific antigens of testicular origin and twelve seminal plasma antigens which coated the spermatozoa during passage through the reproductive tract. Two of the sperm-coating antigens originated in the testis, two in the epididymis and eight above the level of the vas deferens. Relationships between sperm-coating antigens and capacitation, and sperm-coating antigens and prevention of immunologically induced aspermatogenesis or immunologically induced infertility in the female were proposed.

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Print ISSN:
1470-1626
Online ISSN:
1741-7899