Daily injections of various commercial preparations of melatonin into immature female rats yielded different results. Melatonin obtained from Regis and Sigma resulted in decreased ovarian and uterine weights when compared to controls, while melatonin obtained from Calbiochem and Nutritional Biochemicals did not alter ovarian or uterine weights. No change was noted in anterior pituitary weights in any of the groups. At present, the explanation for these differences is unknown.
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