A DIFFERENCE IN THE IMMUNOGLOBULIN CONTENT OF SEMINIFEROUS TUBULE FLUID AND RETE TESTIS FLUID OF THE RAT

in Reproduction

Seminiferous tubule fluid of the testis is unique in many respects, due to the existence of a barrier mechanism which prevents the entry of various endogenous and administered substances (for references, see Setchell, 1970). Recent studies on ram rete testis fluid obtained by catheter implantation technique (Voglmayr, Waites & Setchell, 1966), suggest that all the individual serum proteins are present in the rete testis fluid but in much lower concentrations. The existence of a specific protein was reported by Johnson & Setchell (1968). Assuming that the rete testis fluid might represent the fluid secreted by the seminiferous tubules, Johnson & Setchell (1968) came to the conclusion that a very little immunoglobulin does enter into the seminiferous tubule fluid, immunoglobulin being observed in the immunoelectrophoretic study of the rete testis fluid. However, in

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