EFFECT OF DECIDUAL CELL-INDUCING STIMULI ON THE PASSAGE OF SODIUM INTO THE UTERINE LUMEN OF THE RAT
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Summary.
The rate of passage of intravenously injected [22Na]sodium into the perfused uterine lumen of the rat was measured in vivo on the day after the application of decidual cell-inducing stimuli, i.e. the injection of arachis oil or the insertion of a thread into the uterine lumen.
The oil injection induced a decidual cell reaction and decreased the rate of passage of22Na by some 50% when injected on Day 5 of pseudopregnancy. By contrast, it produced neither of these effects when injected at metoestrus, suggesting that the decrease in rate is associated with decidual cell formation.
The presence of a thread in the uterine lumen for 1 day increased the rate markedly both in horns threaded on Day 5 of pseudopregnancy and at metoestrus. When the thread was present for longer periods, the rate declined and the uterus became unresponsive to further threading.
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