Injections of a mixture of fsh and lh into hens caused premature ovulation although each hormone was ineffective when injected alone at the same dose level. The incidence of premature ovulation increased when an ineffective dose of fsh was given with a mildly effective dose of lh. The increase was also found when fsh was injected either immediately after or 1 hr after the injection of lh. The results suggest that fsh augments the action of lh to induce ovulation in the hen.
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