Extracts of tissues and secretions of women were examined by immunoelectrophoresis with an antiserum against human seminal plasma. Of the twenty-three detected seminal plasma antigens, seven were found in blood serum, and ten antigens not detected in blood serum were found in other female tissues and secretions. Milk was found to contain one non-serum seminal plasma antigen; saliva, urine, vagina and ovary each contained two; cervical mucus and kidney each contained three; nasal secretion, cervix, endometrium, and Fallopian tubes each contained four; and gastric fluid contained five such antigens. It is suggested that women may avoid adverse immunological reactions to seminal plasma because its antigens are not foreign to them.
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