HISTOCHEMICAL LOCALIZATION OF ACID UTERINE AMINOACYLNAPHTHYLAMIDASES IN EARLY PREGNANCY AND IN DIFFERENT HORMONAL STATES OF THE MOUSE
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Summary.
Two different aminoacylnaphthylamidase reactions in the mouse uterus are described, a particulate one in the glandular epithelium and a vacuolar one in the luminal epithelium and at the implantation sites. Maximum epithelial enzyme activity was observed on Day 5 of pregnancy or after 6 days' progesterone treatment of the spayed mouse. No further increase was achieved after oestradiol superimposed on progesterone treatment. At implantation sites on Day 8, the activity was mainly localized antimesometrially to the embryo. It is suggested that the uterine epithelial activity contributes to the breakdown of uterine secretion before the attachment reaction.
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