A COMPARISON OF THE SPECIFIC EFFECTS OF OESTRIOL AND OESTRADIOL ON THE UTERINE BODY AND CERVIX OF THE SPAYED RAT

in Reproduction
Authors:
F. D. JOHNSTONE
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R. CULLEN
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G. YOUNGSON
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Summary.

The theory that oestriol and oestradiol have specific patterns of effect on the lower and upper reproductive tracts was investigated in the spayed rat. At dose levels which produced similar increases in uterine wet weight, there was no difference in decrease in tensile strength of the cervix. From a review of the literature, it is suggested that oestriol may exert a pronounced effect on the cervix in late pregnancy, but not because of any specific `polar' effect.

 

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