IMMUNIZATION OF RABBITS AGAINST FSH AND EFFECTS ON THE ZONA PELLUCIDA
in ReproductionSearch for other papers by R. MONASTIRSKY in
Current site
Google Scholar
PubMed
Search for other papers by ELSA B. SCHUCHNER in
Current site
Google Scholar
PubMed
Search for other papers by R. B. DEU in
Current site
Google Scholar
PubMed
Summary.
The effects of active FSH immunization on the ovarian morphology of adult rabbits were studied. Rabbits were immunized intradermally in multiple sites with antibodies to ovine FSH. Both the macroscopic morphology and the weight of the ovaries of the experimental rabbits were similar to those of the controls. Multiple branched projections of the granulosa cells were seen in the experimental rabbits. These projections had higher electron density than the rest of the cell. The zona pellucida was not formed although the growing follicles were large enough to have a completely formed layer. Disturbance of the metabolism of the follicular cells, due to the lack of endogenous FSH, could explain this abnormality.
Reproduction is committed to supporting researchers in demonstrating the impact of their articles published in the journal.
The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.
More information is on the Reasons to publish page.
| Sept 2018 onwards | Past Year | Past 30 Days | |
|---|---|---|---|
| Full Text Views | 135 | 45 | 21 |
| PDF Downloads | 52 | 15 | 3 |
Online ISSN: 1741-7899
Print ISSN: 1470-1626
Strengthening biomedical communities
to advance science and health
CONTACT US
Bioscientifica Ltd | Starling House | 1600 Bristol Parkway North | Bristol BS34 8YU | UK
Bioscientifica Ltd | Registered in England no 3190519