AN EFFECT OF THE FEMALE GENOTYPE ON SPERM TRANSPORT IN MICE

in Reproduction
Authors:
A. NICOL
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ANNE McLAREN
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Differences between inbred strains of mice in the timing of the first cleavage division were first detected by Braden (1958). One such difference, analysed by Krzanowska (1964), was found to be due to the genetic constitution of the male. In comparisons among two inbred strains, an F1 group and an outbred strain, fertilization occurred earlier after matings with F1 than with inbred males, and earlier still with outbred males, irrespective of the genotype of the female.

On the other hand, McLaren & Bowman (1973) found that a difference in the timing of development of C57BL and C3H embryos was mediated entirely through the mother. Development in C57BL females was 3 to 4 hr ahead of development in C3H females, whether the females were mated to males of their own or the other strain. The difference

 

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