CHANGES WITH AGE IN THE OCCURRENCE OF C19 STEROIDS IN THE TESTIS AND SUBMAXILLARY GLAND OF THE BOAR

W. D. BOOTH

doi:10.1530/jrf.0.0420459

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CHANGES WITH AGE IN THE OCCURRENCE OF C₁₉ STEROIDS IN THE TESTIS AND SUBMAXILLARY GLAND OF THE BOAR

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W. D. BOOTH

W. D. BOOTH
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DOI:: https://doi.org/10.1530/jrf.0.0420459

Volume/Issue:: Volume 42: Issue 3

Page Range:: 459–472

Article Type:: Research Article

Online Publication Date:: Mar 1975

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Summary.

After extraction from the testes of boars of different ages, C₁₉ steroids including 16-androstenes were determined by gas-liquid chromatography. Similarly, 16-androstenes were determined in the submaxillary glands of these boars. A high concentration of testosterone was found in the testes of 84-day-old fetuses, and this might be significant in the differentiation of male behaviour. The amount of testosterone exceeded that of androstenedione during postnatal development, and dehydroepiandrosterone and 5-androstenediol as free and sulphates were found in high concentrations particularly in postpubertal boars, suggesting that the 5-ene pathway for the synthesis of testosterone might be important. There was a change in the predominance of individual 16-androstenes in the testis during development, which closely paralleled the sequence for the biosynthesis of these compounds proposed from previous studies in vitro. Whereas the amount of 5α-androst-16-en-3β-ol exceeded that of 5α-androst-16-en-3α-ol in postpubertal testes, 5α-androst-16-en-3α-ol was predominant in the submaxillary glands at all ages. The high concentration of 16-androstenes found in the mature boar, are discussed in relation to their release as pheromones and as factors responsible for taint in boar meat.

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