NUCLEIC ACID METABOLISM OF CELLS OF THE LUMINAL EPITHELIUM AND STROMA OF THE RAT UTERUS DURING EARLY PREGNANCY
in ReproductionSearch for other papers by P. J. HEALD in
Current site
Google Scholar
PubMed
Search for other papers by J. E. O'GRADY in
Current site
Google Scholar
PubMed
Search for other papers by ANNE O'HARE in
Current site
Google Scholar
PubMed
Search for other papers by MAUREEN VASS in
Current site
Google Scholar
PubMed
Summary.
The uptake of [5-3H]uridine into RNA and DNA of the cells of the uterine luminal epithelium, stroma and myometrium of the rat has been studied in early pregnancy using a technique for separation of the cell fractions before quantitative analysis. Comparisons of the metabolism between the pregnant and pseudopregnant horn of the unilaterally ovariectomized rat has shown that RNA and DNA synthesis are markedly increased by 04.00 hours on the morning of Day 5 in the pregnant horn. This increased metabolism occurs in all cell fractions and before the zona pellucida is shed. The results are discussed in relation to the onset of the decidual response.
Reproduction is committed to supporting researchers in demonstrating the impact of their articles published in the journal.
The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.
More information is on the Reasons to publish page.
| Sept 2018 onwards | Past Year | Past 30 Days | |
|---|---|---|---|
| Full Text Views | 151 | 73 | 2 |
| PDF Downloads | 59 | 20 | 0 |
Online ISSN: 1741-7899
Print ISSN: 1470-1626
Strengthening biomedical communities
to advance science and health
CONTACT US
Bioscientifica Ltd | Starling House | 1600 Bristol Parkway North | Bristol BS34 8YU | UK
Bioscientifica Ltd | Registered in England no 3190519