17-HYDROXYANDROGENS AND OESTROGENS IN THE PLASMA OF NORMAL AND INFERTILE MEN
in ReproductionSearch for other papers by M. S. WALKER in
Current site
Google Scholar
PubMed
Search for other papers by J. K. GRANT in
Current site
Google Scholar
PubMed
Search for other papers by R. SCOTT in
Current site
Google Scholar
PubMed
Search for other papers by J. SINCLAIR in
Current site
Google Scholar
PubMed
University Department of Steroid Biochemistry, and Department of Urology, Royal Infirmary, Glasgow G4 OSF (Received 5th February 1975)
Androgens, particularly testosterone, have long been held to be controlling factors in spermatogenesis (Steinberger & Ducket, 1967). Oestrogens have been shown to influence the output of pituitary gonadotrophins and thus cause Leydig cell atrophy. They also affect germinal cells in the seminiferous tubules directly (de la Balze et al., 1962).
In the present study, we have attempted to correlate the plasma concentrations of 17-hydroxyandrogens (17-OHA) and oestradiol-17 β with the sperm counts and testicular histology of 134 men. All the men were referred to the infertility clinic with a history of at least 2 years of childless marriage during which regular intercourse, without contraception, had taken place.
On the patient's initial visit to the clinic, 10 ml peripheral venous blood were withdrawn for steroid assays. The patients were instructed to collect semen
Reproduction is committed to supporting researchers in demonstrating the impact of their articles published in the journal.
The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.
More information is on the Reasons to publish page.
| Sept 2018 onwards | Past Year | Past 30 Days | |
|---|---|---|---|
| Full Text Views | 297 | 198 | 2 |
| PDF Downloads | 72 | 17 | 0 |
Online ISSN: 1741-7899
Print ISSN: 1470-1626
Strengthening biomedical communities
to advance science and health
CONTACT US
Bioscientifica Ltd | Starling House | 1600 Bristol Parkway North | Bristol BS34 8YU | UK
Bioscientifica Ltd | Registered in England no 3190519