Gonadotrophin-induced changes in the Sertoli cells of the immature mouse testis

in Reproduction
Author:
A. G. Davies
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DOI:
https://doi.org/10.1530/jrf.0.0470083
Volume/Issue:
Volume 47: Issue 1
Page Range:
83–85
Article Type:
Research Article
Online Publication Date:
May 1976
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Summary.

Highly purified preparations of human pituitary gonadotrophins were administered to immature male mice daily for 3 days. The mice were killed on the 9th day after birth and the testes were prepared for electron microscopy. FSH treatment caused an increase in the mass of Sertoli cell cytoplasm, and FSH and LH increased the size of mitochondria in these cells. The number of polysomes in each Sertoli cell was increased after FSH treatment, but the number of ribosomes/polysome was not affected.

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Print ISSN:
1470-1626
Online ISSN:
1741-7899