Czechoslovak Academy of Sciences, Institute of Animal Physiology and Genetics, Department of Genetics, Liběchov, Czechoslovakia
Prostaglandin F-2α (PGF-2α) and its analogues have been proposed as agents for control of the oestrous cycle by inducing regression of the functional CL in several mammals, but few data are available on fertility at the synchronized oestrus in cattle. The first successful pregnancy was reported by Rowson, Tervit & Brand (1972) and encouraging results with small numbers of animals have since been published (Inskeep, 1973; Philipsen & Rasbech, 1973; Roche, 1974). Experiments on a larger scale were evaluated by Lauderdale et al. (1974). Except for Rowson et al. (1972), who used intrauterine application, the above authors all administered PGF-2α intramuscularly.
Although Nakahara, Kaneda, Domeki & Yamauchi (1974) and Ohta, Umezu & Takeuchi (1974) reported satisfactory results after intrauterine administration of PGF-2α through the cervix, Henricks, Long, Hill & Dickey (1974) observed lower fertility.
The
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