Protein synthesis in vitro by pig blastocyst tissue before attachment
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A.R.C. Institute of Animal Physiology, Babraham, Cambridge CB2 4AT, U.K.
In pregnancy the prolongation of the life of the CL and its secretion of progesterone normally depends upon the presence of an embryo. The embryo signals its presence by some active process, and in the pig the onset of oestrogen synthesis between Days 10 and 12 (Perry, Heap & Amoroso, 1973; Heap, Perry, Gadsby & Burton, 1975; Perry, Heap, Gadsby & Burton, 1976) coincides with the time of maternal recognition of pregnancy (Dhindsa & Dziuk, 1968). The onset of steroidogenesis precedes any permanent attachment between the trophoblast and uterine wall, as intimate contact between fetal and maternal epithelia by interlocking microvilli is not established until Day 18. During this period the blastocyst enlarges from about 2 mm in diameter at Day 10 to a tubular, bilaminar structure about 1000 mm in length by Day 14-16. In this study we have
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