Evidence for a physiological role of prostaglandins in oviposition by the hen

in Reproduction
Authors:
F. Hertelendy
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H. V. Biellier
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Summary. A single oral dose of indomethacin (25 mg) given 2–4 h before expected oviposition delayed oviposition by about 12 h and suppressed plasma PGE levels by about 90%. Intrauterine injection of PGE-1 (0·2–0·4 μg/hen) to 12 hens pretreated with 25 mg indomethacin induced oviposition in all birds in about 7½ min. Passive immunization with goat antiserum to PGE-1 delayed oviposition (69%) in 4 hens. It is concluded that prostaglandins play a functional role in oviposition.

 

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