Effects of castration, 5α-dihydrotestosterone and cyproterone acetate on enzyme activity in the mouse epididymis

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Summary. The influence of castration, androgen replacement therapy and cyproterone acetate on the activity of β-glucuronidase, acid and alkaline phosphatases and glucose-6-phosphate dehydrogenase was studied in the caput, corpus and cauda epididymidis of the mouse. The results add further evidence that the epididymis is not uniform but has regional differences in activity. Thus β-glucuronidase was found to be androgen-dependent only in the cauda epididymidis, whereas glucose-6-phosphate dehydrogenase was under androgenic control in the caput epididymidis. The response of alkaline and acid phosphatases to castration and to androgen replacement was different in different segments.


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    Society for Reproduction and Fertility


Sept 2018 onwards Past Year Past 30 Days
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