Polyamine inhibition of the conversion of human proacrosin to acrosin

in Reproduction

Summary. The conversion of human proacrosin to acrosin was inhibited by polyamines. The order of effectiveness was spermine > spermidine > cadaverine > putrescine > 1,3-diaminopropane. These results are similar to those obtained for the conversion of boar proacrosin to acrosin. Unlike the effects on boar acrosin, however, polyamines did not affect the esterolytic activity of human acrosin but had a slight stimulatory effect on the proteolytic activity of human acrosin.

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     An official journal of

    Society for Reproduction and Fertility


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