Morphometric analysis of the visceral yolk sac endoderm in the rat in vivo and in vitro
in ReproductionSearch for other papers by M. Gupta in
Current site
Google Scholar
PubMed
Search for other papers by A.P. Gulamhusein in
Current site
Google Scholar
PubMed
Search for other papers by F. Beck in
Current site
Google Scholar
PubMed
Summary. Rat embryos together with their visceral yolk sac were grown in vitro during the early period of organogenesis from days 9·5 to 11·5 and the ultrastructural morphology of the visceral yolk sac cells was compared with that in vivo at the beginning and at the end of the culture period. Identical areas of the visceral yolk sac endodermal cells were analysed morphometrically. A measure of the functional activity was obtained by comparison of the volume density and surface density of the vacoular system. At 9·5 and 11·5 days, the values obtained were virtually identical for yolk sacs in vivo and in vitro. At 9·5 days, the volume and surface density of the endocytotic vacuoles in the embryonic endoderm was significantly lower than in the visceral yolk sac endoderm.
It is concluded that the digestive function of the yolk sac is almost certainly identical in culture and in vivo and that the cells of the embryonic endoderm do not take a significant part in embryonic nutrition.
Reproduction is committed to supporting researchers in demonstrating the impact of their articles published in the journal.
The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.
More information is on the Reasons to publish page.
| Sept 2018 onwards | Past Year | Past 30 Days | |
|---|---|---|---|
| Full Text Views | 143 | 48 | 20 |
| PDF Downloads | 64 | 19 | 0 |
Online ISSN: 1741-7899
Print ISSN: 1470-1626
Strengthening biomedical communities
to advance science and health
CONTACT US
Bioscientifica Ltd | Starling House | 1600 Bristol Parkway North | Bristol BS34 8YU | UK
Bioscientifica Ltd | Registered in England no 3190519