Antifertility action of a sterol sulphate in the rabbit
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Summary. Introduction of 0·5 mg β-sitosteryl sulphate, a potent acrosin inhibitor, in K-Y jelly into the vagina of rabbits before coitus lowered the pregnancy rate. Cholesteryl sulphate had no effect. A 1·5 × 10 mm silicone rod containing 10% (w/w) β-sitosteryl sulphate released 1–2 μg of compound per day over a 16-day period in vitro. When such implants were placed in rabbit uteri, there was a significant reduction in the numbers of embryos in those horns.
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| Sept 2018 onwards | Past Year | Past 30 Days | |
|---|---|---|---|
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