Effect of surgery and efferent duct ligation on testicular blood flow and testicular steroidogenesis in the rat

in Reproduction
Authors:
J. M. Wang
Search for other papers by J. M. Wang in
Current site
Google Scholar
PubMed
Close
,
C. H. Gu
Search for other papers by C. H. Gu in
Current site
Google Scholar
PubMed
Close
,
L. Tao
Search for other papers by L. Tao in
Current site
Google Scholar
PubMed
Close
, and
X. L. Wu
Search for other papers by X. L. Wu in
Current site
Google Scholar
PubMed
Close
Free access

Sign up for journal news

Summary. A moderate reduction in testicular blood flow was observed in both testes 24 h after unilateral efferent duct ligation without any corresponding change in testosterone secretion as indicated in the peripheral blood, in testicular venous blood, or in testicular tissue fluid. At 21 days a pronounced unilateral decrease in blood flow was associated with the extensive degeneration of tubules in the testis on the ligated side. These changes were also associated with decreased testosterone secretion by the testis on the ligated side, although Leydig cell function was not abolished since testosterone in the tissue increased rather than decreased. It is therefore concluded that testicular blood flow may play an important role in the changes of testosterone secretion that follow unilateral efferent duct ligation.

 

  • Collapse
  • Expand