Mann (1951, 1954) showed that meso-inositol constituted a major component of the seminal vesicle secretion. Hartree (1957) found that in the seminal plasma of man, pig and rabbit inositol existed mainly in the free form, but a substantial percentage of the total inositol was in a combined form in that of cattle, horse and sheep. The function of meso-inositol in the secretions of the male reproductive tract is obscure. In contrast to fructose, it does not appear to influence the motility or respiration of spermatozoa, nor does it influence fructolysis. Mann (1954) has suggested that it may play a part in the maintenance of the osmotic pressure in the seminal vesicle secretion. Hartree (1957) has postulated that it may be an intermediate in the conversion of glucose to fructose; a formation of inositol from glucose has indeed
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