Replication status of the fragile X chromosome and its implications for reproductive performance in the Indian mole rat (Nesokia indica)

in Reproduction

Summary. In all fertile females the fragile X chromosome was almost always late replicating (inactive) in an average 82% of cells whereas in infertile females, it was early replicating (active) in about the same percentage of cells. These observations strongly suggest a correlation between the replication (activity) status of the fragile X chromosome and reproductive performance.

Keywords: fragile X chromosome; replication status; reproduction; Indian mole rat

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    Society for Reproduction and Fertility

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