Concentrations of progesterone and oxytocin receptors in endometrium of postpartum cows expected to have a short or normal oestrous cycle
in ReproductionSearch for other papers by W. G. Zollers Jr in
Current site
Google Scholar
PubMed
Search for other papers by H. A. Garverick in
Current site
Google Scholar
PubMed
Search for other papers by M. F. Smith in
Current site
Google Scholar
PubMed
Search for other papers by R. J. Moffatt in
Current site
Google Scholar
PubMed
Search for other papers by B. E. Salfen in
Current site
Google Scholar
PubMed
Search for other papers by R. S. Youngquist in
Current site
Google Scholar
PubMed
Luteal lifespan is short after first postpartum ovulation in early-weaned beef cows unless cows are pretreated with a progestogen. Regression of the short-lived corpus luteum in the postpartum beef cow is due to a premature release of prostaglandin F2α (PGF2α) from the uterus. The premature release of PGF2α may be mediated through lower concentrations of receptors for progesterone, higher concentrations of oxytocin receptors, or both, in the endometrium. Thirty-one beef cows were randomly assigned to four groups at parturition. Calves from cows assigned to the short cycle group (n = 6; control) and the short cycle/endometrium group (n = 10) were weaned at 30–32 days post partum. Cows in the normal cycle group (n = 5; control) and the normal cycle/endometrium group (n = 10) received norgestomet implants for 9 days beginning 21–23 days post partum and calves were weaned at implant insertion. Duration of oestrous cycle (x ± sem; P < 0.01) following first postpartum ovulation for the short cycle group was 11.5 ± 1.9 days compared with 18.8 ± 0.6 days for the normal cycle group. On day 5 following first postpartum ovulation, cows in the short cycle/endometrium and the normal cycle/endometrium groups were hysterectomized and endometrial tissue collected for measurement of progesterone and oxytocin receptors. Mean number of total progesterone receptors per cell was lower (P < 0.05) in the short cycle/endometrium group than in the normal cycle/endometrium group. Mean concentration of oxytocin receptors (fmol mg−1 protein) in the short cycle/endometrium group was higher (P < 0.05) than that in the normal cycle/endometrium group. In conclusion, uterine receptor populations for progesterone and oxytocin may influence the timing of PGF2α secretion during short oestrous cycles.
Reproduction is committed to supporting researchers in demonstrating the impact of their articles published in the journal.
The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.
More information is on the Reasons to publish page.
| Sept 2018 onwards | Past Year | Past 30 Days | |
|---|---|---|---|
| Full Text Views | 393 | 121 | 18 |
| PDF Downloads | 204 | 80 | 12 |
Online ISSN: 1741-7899
Print ISSN: 1470-1626
Strengthening biomedical communities
to advance science and health
CONTACT US
Bioscientifica Ltd | Starling House | 1600 Bristol Parkway North | Bristol BS34 8YU | UK
Bioscientifica Ltd | Registered in England no 3190519