Segmental distribution of α-glucosidase, ornithine decarboxylase and polyamines in the human epididymis

in Reproduction
Authors:
K. Purvis
Search for other papers by K. Purvis in
Current site
Google Scholar
PubMed Close
and
I. Egdetveit
Search for other papers by I. Egdetveit in
Current site
Google Scholar
PubMed Close
DOI:
https://doi.org/10.1530/jrf.0.0970575
Volume/Issue:
Volume 97: Issue 2
Page Range:
575–580
Article Type:
Research Article
Online Publication Date:
Mar 1993
Free access

Sign up for journal news

Regional differences in the total activities of the epididymal secretory parameter, α-glucosidase, were demonstrated in the 20 000 g supernatants of human epididymal homogenates. A comparison of the enzymic activities in the supernatants and the washings from 12 one centimetre segments of human epididymides indicated an activity peak in segments 3–4 which appeared to be largely intracellular and which presumably reflects the acidic isoenzyme. A second peak in the caudal region, the segmental localization of which was more variable and differed in post-mortem and operation specimens, appeared to be primarily intraluminal. The activities of ornithine decarboxylase (ODC), the rate-limiting enzyme in the polyamine pathway, also exhibited regional differences with higher activities in relatively short segments in both caput and caudal portions. Corresponding alterations were also found in the tissue concentrations of the enzyme products, spermidine and spermine. The increased intracellular activities of ODC and α-glucosidase in the distal caput segments presumably reflect the transition of epithelium from the efferent to the epididymal ducts.

Reproduction is committed to supporting researchers in demonstrating the impact of their articles published in the journal.

The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media.

More information is on the Reasons to publish page.

Sept 2018 onwards Past Year Past 30 Days
Full Text Views 201 100 0
PDF Downloads 78 39 0

 

  • Collapse
  • Expand
Print ISSN:
1470-1626
Online ISSN:
1741-7899