Replication status of the fragile X chromosome and its implications for reproductive performance in the Indian mole rat (Nesokia indica)

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Authors:
Rita Tewari
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S. R. V. Rao
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DOI:
https://doi.org/10.1530/jrf.0.0910203
Volume/Issue:
Volume 91: Issue 1
Page Range:
203–206
Article Type:
Research Article
Online Publication Date:
Jan 1991
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Summary. In all fertile females the fragile X chromosome was almost always late replicating (inactive) in an average 82% of cells whereas in infertile females, it was early replicating (active) in about the same percentage of cells. These observations strongly suggest a correlation between the replication (activity) status of the fragile X chromosome and reproductive performance.

Keywords: fragile X chromosome; replication status; reproduction; Indian mole rat

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Print ISSN:
1470-1626
Online ISSN:
1741-7899